RNA Details
Disease Name
ventricular dysfunction
Tissue
heart
RNA Symbol
Kl
RNA ID
RNA Type
mRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
NA
Target
NA
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
"Klotho inhibits angiotensin II-induced cardiac hypertrophy, fibrosis, and dysfunction in mice through suppression of transforming growth factor-beta1 signaling pathway"
Year
2019
Function
Klotho prevents ang ii-induced cardiac remodeling and dysfunction through modifying the TGF-beta1-miR-132 axis.